Skip to main content

Table 2 Statistical summary of metrics used in this study

From: Data-driven gated PET/CT: implications for lesion segmentation and quantitation

  PET/ACT DDG-PET DDG-PET/CT
\(\tilde{x }\)± σ Range p \(\tilde{x }\)± σ Range p \(\tilde{x }\)± σ Range p
Metric ratio
Volume 1.00 ± 0.58 0.38–3.38 0.54 0.64 ± 0.26 0.20–1.61 *** 0.74 ± 0.40 0.37–2.39 ***
SUVmax 1.20 ± 0.43 0.90–3.30 *** 1.26 ± 0.23 0.58–1.81 *** 1.66 ± 0.66 1.07–4.48 ***
SUVmean 1.17 ± 0.40 0.93–3.28 *** 1.19 ± 0.18 0.53–1.81 *** 1.55 ± 0.52 1.05–3.50 ***
LG 1.26 ± 1.23 0.46–6.21 * 0.78 ± 0.32 0.11–2.17 *** 1.13 ± 1.12 0.46–7.23 0.19
TLG 1.12 ± 0.32 0.80–2.04 0.41 0.82 ± 0.15 0.54–1.13 ** 1.10 ± 0.38 0.79–2.08 0.34
Metric
CCD 1.6 ± 2.5 0.2–15.1 3.9 ± 3.6‡ 0.3–18.2 *** 4.6 ± 3.8‡ 0.4–21.0 ***
DICE 0.80 ± 0.15 0.26–0.94 0.67 ± 0.18‡ 0–0.94 *** 0.64 ± 0.17‡ 0–0.89 ***
Lesion ΔHU 61.6 ± 311 − 65–906 *** − 8.7 ± 157 − 859–49 * 85.6 ± 352 − 64–953 ***
  1. \(\tilde{x }\) = median, σ = standard deviation, LG = lesion glycolysis, TLG = total lesion glycolysis, CCD = centroid-to-centroid distance (mm), DICE = DICE similarity coefficient, ΔHU = change in mean HU
  2. All metric ratios and tests of significance (p) are relative to baseline PET/CT except for p relative to PET/ACT
  3. CCD, DICE, and ΔHU values are calculated relative to baseline PET/CT lesion contours
  4. *p < 0.01, **p < 0.001, ***p < 0.0001