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EJNMMI Physics
Fig. 2 | EJNMMI Physics

Fig. 2

From: Dosimetric impact of Ac-227 in accelerator-produced Ac-225 for alpha-emitter radiopharmaceutical therapy of patients with hematological malignancies: a pharmacokinetic modeling analysis

Fig. 2

Pharmacokinetic model for radiolabeled antibody. The dotted line corresponds to the distribution volume of IV-administered antibody; ECF = extracellular fluid volume. Compartments 1 and 2 represent the free, (Ab) and antigen-bound antibody (AbAg) states, respectively. Compartment 3 represents internalized AbAg. The figure is adapted from reference [13]

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