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Fig. 2 | EJNMMI Physics

Fig. 2

From: Simple model for estimation of absorbed dose by organs and tumors after PRRT from a single SPECT/CT study

Fig. 2

Patient management using the standard dosimetry protocol versus MLR-based protocol. a Expected kidney absorbed dose after the next PRRT cycle calculated from previous treatment cycles (1 to 3) using the standard (blue stars) or the MLR-based (triangles) protocols. b Management of the 25 patients included in the study based on the kidney cumulative “predicted” absorbed dose using either the standard or the MLR-based protocols with a safety threshold fixed at a 25 Gy. No management decision could be given for patient #19 with both protocols. Horizontal lines separate the different managements of the patient (4 CYCLES: the patient can receive 4 cycles safely, 1 PTS only; 4 CYCLE—2 PTSs: 4 cycles safely, 2 PTSs only; CONSIDER A fourth CYCLE—3 PTSs: consider to administer a fourth cycle based on the probability to exceed 25 Gy after 4 cycles; 3 CYCLES—2 PTSs: 3 cycles safely, 2 PTSs only; CONSIDER A third CYCLE—2 PTSs: consider at maximum a third cycle; STOP TREATMENT—1 cycle: stop after a single cycle). AD = absorbed dose

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