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Table 3 Time integrated activity coefficients, \( \overset{\sim }{a}\left({r}_S,{T}_D\right), \) for each radionuclide and each source region (in h)

From: Radiopharmacokinetic modelling and radiation dose assessment of 223Ra used for treatment of metastatic castration-resistant prostate cancer

Source region 223Ra 219Rn 215Po 211Pb 211Bi 211Po 207TI
Blood 0.89 1.00 1.00 1.11 1.02 0.003 1.01
Other tissues 6.85 6.84 6.84 6.71 6.70 0.02 6.88
Cortical bone surface 9.49 9.42 9.42 9.18 9.18 0.03 9.08
Cortical bone volume 14.14 14.14 14.14 14.30 14.30 0.04 14.26
Trabecular bone surface 11.85 11.77 11.77 11.47 11.47 0.03 11.33
Trabecular bone volume 17.66 17.66 17.66 17.86 17.86 0.05 17.81
Cortical marrow 0.04 0.04 0.04 0.04 0.04 0.0001 0.04
Trabecular marrow 0.44 0.44 0.44 0.45 0.45 0.001 0.45
Kidneys 0.64 0.64 0.64 0.68 0.72 0.002 0.73
Urinary bladder content 0.04 0.04 0.04 0.06 0.08 0.0002 0.08
Liver 5.12 5.11 5.11 5.19 5.22 0.01 5.17
Skin 0.43 0.43 0.43 0.44 0.44 0.001 0.44
Spleen 0.02 0.02 0.02 0.02 0.02 0.0001 0.02
Testes 0.005 0.005 0.005 0.005 0.005 0.0000 0.006
Small intestine content    0.000 0.005 0.007 0.0000 0.002
Right colon content 9.40 9.40 9.40 8.78 8.74 0.02 8.64
Left colon content 9.12 9.12 9.12 9.10 9.10 0.03 9.07
Recto sigmoid content 8.85 8.85 8.85 8.87 8.87 0.03 8.85