Table 4 Absorbed dose coefficients for [¹¹C]-UCB-J determined from three healthy subjects using OLINDA/EXM 2.1, compared to OLINDA/EXM 1.1

4.99E−03

4.84E−03

4.13E−03

4.52E−03 ± 0.56

55%

1.93E−02

1.56E−02

1.13E−02

14.38E−02± 4.35

−6%

1.56E−03

1.65E−03

1.61E−03 ± 0.06

10%

2.63E−03

2.62E−03

2.36E−03

2.49E−03 ± 0.19

n/a

2.93E−03

2.73E−03

1.87E−03

2.35E−03 ± 0.68

n/a

1.28E−02

4.19E−03

7.95E−03

8.22E−03 ± 0.39

9%

3.62E−03

3.18E−03

3.82E−03

3.61E−03 ± 0.30

14%

2.67E−02

1.82E−02

2.46E−02

23.53E−02 ± 1.52

26%

9.32E−03

5.58E−03

6.76E−03

7.11E−03 ± 0.49

8%

8.63E−03

6.52E−03

9.06E−03

8.32E−03 ± 1.05

8%

3.96E−03

3.48E−03

2.62E−03

3.17E−03 ± 0.78

n/a

5.33E−03

4.97E−03

5.82E−03

5.49E−03 ± 0.47

0%

1.60E−02

1.68E−02

7.33E−03

11.87E−02 ± 6.41

1%

1.58E−02

1.54E−02

1.35E−02

14.55E−02 ± 1.49

4%

4.09E−03

3.85E−03

3.80E−03

3.89E−03 ± 0.12

−8%

3.33E−03

3.02E−03

3.18E−03 ± 0.22

68%

4.66E−03

4.16E−03

3.89E−03

4.15E−03 ± 0.37

17%

2.50E−03

2.50

n/a

2.64E−03

2.52E−03

2.00E−03

2.29E−03 ± 0. 41

n/a

4.81E−03

4.55E−03

3.67E−03

4.18E−03 ± 0.71

6%

3.40E−03

3.23E−03

2.88E−03

3.10E−03 ± 0.31

−23%

5.23E−03

5.34E−03

2.80E−03

4.04E−03 ± 1.76

18%

0.00E+00

0.00E+00

1.38E−03

1.38E−03

−3%

2.10E−03

2.17E−03

1.86E−03

2.00E−03 ± 0.19

16%

1.74E−03

1.83E−03

1.57E−03

1.68E−03 ± 0.15

7%

3.12E−02

2.34E−02

1.61E−02

21.70E−02 ± 7.92

−7%

4.56E−03

3.88E−03

0.00E+00

4.22E−03 ± 0.48

12%

3.45E−03

3.20E−03

2.39E−03

2.86E−03 ± 0.66

−1%

6.24E−03

5.07E−03

4.50E−03

5.08E−03 ± 0.82

−6%