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Table 2 Reconstructed activity concentration, inhomogeneity of reconstructed activity concentration in the anatomically oriented ROIs, and median deviation from the reference region for the optimized scan protocol (40 mA, pitch = 1.375, slicing = 3.75 mm)

From: Quantitative imaging of bone remodeling in patients with a unicompartmental joint unloading knee implant (ATLAS Knee System)—effect of metal artifacts on a SPECT-CT-based quantification

Protocol ID Region SPECT [kBq/ml] Pa Inhomogeneity in the slicesb [%] Pc Median deviation from reference [%] Pd
S Plus Femur 186 (183/191)
167‑220
0.019 0.27 (0.00/0.54)
−3.23‑7.53
< 0.0001 −10.08 (−11.53/−7.66)
-19.27‑6.36
< 0.0001
Tibia 189 (182/198)
168‑222
  0.26 (−3.05/3.18)
−4.51‑6.63
< 0.0001 −8.87 (−12.02/−4.28)
−18.78‑7.32
< 0.0001
B Plus Femur 186 (182/191)
166‑220
0.015 0.81 (0.00/0.54)
−3.76‑7.53
< 0.0001 −10.13 (−12.06/−7.71)
-19.79‑6.30
< 0.0001
Tibia 188 (182/198)
168‑222
  −0.26 (−3.05/3.18)
−5.04‑6.63
< 0.0001 −9.16 (−12.06/−4.33)
−18.83‑7.26
< 0.0001
B+ Plus Femur 186 (182/191)
164‑220
0.049 0.00 (−0.40/0.40)
−4.30‑7.53
< 0.0001 −10.13 (−12.06/−7.83)
−20.76‑6.23
< 0.0001
Tibia 187 (181/197)
165‑222
  0.27 (−2.81/3.74)
−5.35‑7.47
< 0.0001 −9.65 (−12.54/−4.81)
−20.28‑7.27
< 0.0001
  1. aSignificance of difference between femur and tibia for the identical reconstruction protocol
  2. bScattering of the observed median in the six different ROIs (n = 6) normalized to the median reconstructed activity concentration estimated over all ROIs in the specific slice (anatomical region)
  3. cSignificant difference between ROIs in the same slice for the identical reconstruction protocol
  4. dSignificance of the difference between reconstructed activity concentration in the anatomical region and reconstructed activity concentration in the reference region