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Table 2 Results of the absorbed dose calculation to normal liver and to tumour

From: EANM Dosimetry Committee series on standard operational procedures for internal dosimetry for 131I mIBG treatment of neuroendocrine tumours

 

First administration

Second administration

Lesion

Liver

Lesion

Liver

Mass (g)

42.8 ± 2.5

711 ± 16

41.4 ± 2.5

711 ± 16

A0 (MBq)

140 ± 23

1010 ± 220

131 ± 30

852 ± 253

Effective half-life (h)

120 ± 22

41.43 ± 10.8

113.7 ± 22.85

39.7 ± 15

Time-integrated activity (MBq·h)

24,280 ± 2389

60,370 ± 5225

21,444 ± 2480

48,853 ± 6741

S value (mGy/MBq·s)

(7.8 ± 0.5) × 10 -4

(0.49 ± 0.01) × 10-4

(8.0 ± 0.5) × 10-4

(0.49 ± 0.01) × 10-4

Absorbed dose (Gy)

68.0 ± 7.8

10.6 ± 1.0

62.1 ± 7.8

8.6 ± 1.2