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Table 5 Absorbed dose to the nucleus corresponding to each added activity for the 4 geometrical modeling assumptions

From: Cellular dosimetry of [177Lu]Lu-DOTA-[Tyr3]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity

Activity

[MBq/ml]

Sphere

[Gy]

TCa (Cy)b

[Gy]

PM (Cy)b

[Gy]

PM (G)b

[Gy]

0.1

0.42 ± 0.05

0.20 ± 0.02

0.14 ± 0.04

0.20 ± 0.07

0.25

1.08 ± 0.13

0.52 ± 0.06

0.35 ± 0.09

0.51 ± 0.18

0.5

2.77 ± 0.30

1.39 ± 0.15

0.92 ± 0.25

1.36 ± 0.47

1

2.63 ± 0.36

1.36 ± 0.18

0.92 ± 0.25

1.33 ± 0.47

2.5

5.64 ± 0.96

2.95 ± 0.47

2.04 ± 0.60

2.86 ± 1.08

  1. a TC=Truncated cone. b The localization of the internalized source is indicated in parenthesis