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Fig. 3 | EJNMMI Physics

Fig. 3

From: Dosimetry after peptide receptor radionuclide therapy: impact of reduced number of post-treatment studies on absorbed dose calculation and on patient management

Fig. 3

Management of the 25 patients included in the study based on the kidney cumulative dose “predicted” after one, two, or three post-treatment scan(s) (PTS) and calculated either by using the standard protocol or by using the (t1, t3) or (t2, t3) “2 time-points” protocols with a safety threshold fixed at a 25 Gy and b 30 Gy. Each color bar represents different protocol. Horizontal lines delimit the different managements of the patient (4 CYCLES: the patient can receive 4 cycles of treatment safely, 1 PTS only; 4 CYCLE—2 PTS: the patient can receive 4 cycles of treatment safely, 2 PTS only; CONSIDER A fourth CYCLE—3 PTS: consider to administer a fourth cycle of treatment based on the probability to exceed the safety threshold after 4 cycles; 3 CYCLES—2 PTS: the patient can receive only 3 cycles of treatment safely, 2 PTS only; CONSIDER A third CYCLE—2 PTS: consider to administer at maximum a third cycle of treatment based on the probability to exceed the safety threshold after 3 cycles; STOP TREATMENT—1 cycle: stop treatment after a single cycle of treatment)

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