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Table 1 Absorbed doses (μGy) in the brain, lung, liver, spleen, pancreas, and kidney obtained from RT-PHITS and OLINDA 2.0. The data are the mean value and standard deviation (S.D.) of the four volunteers with the injection of NKO-035 virtually labeled with 1 MBq of 18F, 211At, 131I, or 177Lu

From: Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model

 

18F

211At

131I

177Lu

RT-PHITS

OLINDA

RT-PHITS

OLINDA

RT-PHITS

OLINDA

RT-PHITS

OLINDA

Mean

S.D.

Mean

S.D.

Mean

S.D.

Mean

S.D.

Mean

S.D.

Mean

S.D.

Mean

S.D.

Mean

S.D.

Brain

4.49

0.83

4.31

0.85

104

28.8

108

30.6

7.15

2.22

6.81

2.06

3.44

1.12

3.50

1.15

Lung

8.36

0.82

8.06

0.68

170

23.5

174

19.3

9.20

1.49

9.02

1.24

4.51

0.72

4.49

0.55

Liver

9.40

0.50

9.10

0.53

127

6.07

137

10.3

8.67

0.40

9.20

1.52

3.40

0.15

3.64

0.34

Spleen

7.56

0.60

7.80

0.72

99.4

8.92

120

16.0

7.06

0.45

8.80

1.50

2.75

0.21

3.28

0.46

Pancreas

12.0

0.86

9.90

1.01

156

20.3

161

23.7

11.2

1.10

11.07

2.02

4.25

0.55

4.29

0.64

Kidney

26.4

9.67

27.7

5.94

547

246

673

158

27.8

10.3

30.1

4.31

14.0

6.15

16.7

3.52