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Table 1 Absorbed doses (μGy) in the brain, lung, liver, spleen, pancreas, and kidney obtained from RT-PHITS and OLINDA 2.0. The data are the mean value and standard deviation (S.D.) of the four volunteers with the injection of NKO-035 virtually labeled with 1 MBq of 18F, 211At, 131I, or 177Lu

From: Individual dosimetry system for targeted alpha therapy based on PHITS coupled with microdosimetric kinetic model

  18F 211At 131I 177Lu
RT-PHITS OLINDA RT-PHITS OLINDA RT-PHITS OLINDA RT-PHITS OLINDA
Mean S.D. Mean S.D. Mean S.D. Mean S.D. Mean S.D. Mean S.D. Mean S.D. Mean S.D.
Brain 4.49 0.83 4.31 0.85 104 28.8 108 30.6 7.15 2.22 6.81 2.06 3.44 1.12 3.50 1.15
Lung 8.36 0.82 8.06 0.68 170 23.5 174 19.3 9.20 1.49 9.02 1.24 4.51 0.72 4.49 0.55
Liver 9.40 0.50 9.10 0.53 127 6.07 137 10.3 8.67 0.40 9.20 1.52 3.40 0.15 3.64 0.34
Spleen 7.56 0.60 7.80 0.72 99.4 8.92 120 16.0 7.06 0.45 8.80 1.50 2.75 0.21 3.28 0.46
Pancreas 12.0 0.86 9.90 1.01 156 20.3 161 23.7 11.2 1.10 11.07 2.02 4.25 0.55 4.29 0.64
Kidney 26.4 9.67 27.7 5.94 547 246 673 158 27.8 10.3 30.1 4.31 14.0 6.15 16.7 3.52