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Table 3 Time-integrated activity coefficient (Bq-h/Bq) for input to IDAC-Dose 2.1 for adult male model calculated using OLINDA/EXM version 1.1 for free 211At and 211At-MABG in the main target organs. It was calculated by extrapolation from the distribution data of mice

From: Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Source organ

211At-Free

211At-MABG

Adipose

1.49E+00

1.03E+00

Adrenal gland

1.17E−03

6.13E−03

Brain

1.67E−02

5.85E−03

Blood

3.57E−01

9.92E−02

Cortical bone mineral, volume

2.03E−01

1.31E−01

Heart wall

3.62E−02

1.17E−01

Kidney

3.09E−02

3.14E−02

Left colon wall

1.20E−02

1.77E−02

Liver

1.03E−01

2.13E−01

Lung

3.86E−01

2.11E−01

Pancreas

1.09E−02

1.04E−02

Red marrow

2.56E−02

6.97E−03

Right colon wall

1.20E−02

1.77E−02

Salivary gland

4.64E−02

2.69E−02

Small intestine wall

8.72E−02

1.12E−01

Spleen

3.69E−02

2.73E−02

Stomach wall

8.66E−02

2.75E−02

Testis

6.04E−03

1.70E−03

Thyroid

6.69E−02

1.83E−02

Trabecular bone mineral, volume

5.08E−02

3.27E−02