Skip to main content

Table 3 Time-integrated activity coefficient (Bq-h/Bq) for input to IDAC-Dose 2.1 for adult male model calculated using OLINDA/EXM version 1.1 for free 211At and 211At-MABG in the main target organs. It was calculated by extrapolation from the distribution data of mice

From: Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Source organ 211At-Free 211At-MABG
Adipose 1.49E+00 1.03E+00
Adrenal gland 1.17E−03 6.13E−03
Brain 1.67E−02 5.85E−03
Blood 3.57E−01 9.92E−02
Cortical bone mineral, volume 2.03E−01 1.31E−01
Heart wall 3.62E−02 1.17E−01
Kidney 3.09E−02 3.14E−02
Left colon wall 1.20E−02 1.77E−02
Liver 1.03E−01 2.13E−01
Lung 3.86E−01 2.11E−01
Pancreas 1.09E−02 1.04E−02
Red marrow 2.56E−02 6.97E−03
Right colon wall 1.20E−02 1.77E−02
Salivary gland 4.64E−02 2.69E−02
Small intestine wall 8.72E−02 1.12E−01
Spleen 3.69E−02 2.73E−02
Stomach wall 8.66E−02 2.75E−02
Testis 6.04E−03 1.70E−03
Thyroid 6.69E−02 1.83E−02
Trabecular bone mineral, volume 5.08E−02 3.27E−02