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Table 1 Time-integrated activity coefficient (Bq-h/Bq) for 25 g mouse model calculated using OLINDA/EXM version 1.1 for free 211At and 211At-MABG in the main target organs. Data are based on biodistribution in mouse organs

From: Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice

Source organ 211At-Free 211At-MABG
Brain 1.17E−02 3.90E−03
LLI* contents 5.93E−02 7.99E−02
Small intestine 2.92E−01 3.42E−01
Stomach contents 2.02E−01 5.89E−02
Heart contents 2.03E−02 5.50E−03
Kidney 1.08E−01 9.67E−02
Liver 1.83E−01 3.81E−01
Lung 1.15E−01 5.99E−02
Pancreas 3.05E−02 2.90E−02
Cortical bone 3.24E−01 2.02E−01
Spleen 5.02E−02 3.12E−02
Testis 4.12E−02 1.18E−02
Thyroid 1.49E−01 4.02E−02
Total body 1.56E+00 1.08E+00
  1. *LLI low large intestine