Table 1 Time-integrated activity coefficient (Bq-h/Bq) for 25 g mouse model calculated using OLINDA/EXM version 1.1 for free 211At and 211At-MABG in the main target organs. Data are based on biodistribution in mouse organs
Source organ | 211At-Free | 211At-MABG |
|---|---|---|
Brain | 1.17E−02 | 3.90E−03 |
LLI* contents | 5.93E−02 | 7.99E−02 |
Small intestine | 2.92E−01 | 3.42E−01 |
Stomach contents | 2.02E−01 | 5.89E−02 |
Heart contents | 2.03E−02 | 5.50E−03 |
Kidney | 1.08E−01 | 9.67E−02 |
Liver | 1.83E−01 | 3.81E−01 |
Lung | 1.15E−01 | 5.99E−02 |
Pancreas | 3.05E−02 | 2.90E−02 |
Cortical bone | 3.24E−01 | 2.02E−01 |
Spleen | 5.02E−02 | 3.12E−02 |
Testis | 4.12E−02 | 1.18E−02 |
Thyroid | 1.49E−01 | 4.02E−02 |
Total body | 1.56E+00 | 1.08E+00 |