Evaluation of block-sequential regularized expectation maximization reconstruction of 68Ga-DOTATOC, 18F-fluoride, and 11C-acetate whole-body examinations acquired on a digital time-of-flight PET/CT scanner

EJNMMI Physics

Table 2 Summary of BSREM β-values that resulted in similar image quality measure, either noise or SNR, as full scan duration OSEM

Image quality parameter	Scan duration (% of OSEM full scan duration)	BSREM β-value
Image quality parameter	Scan duration (% of OSEM full scan duration)	⁶⁸Ga-DOTATOC	¹⁸F-fluoride	¹¹C-acetate
Noise^*	100%	400	533	267
Noise	50%	> 533	> 533	400
SNR	100%	200	300	< 133
SNR	50%	400	> 533	133

^*Noise was defined as SUV_SD divided by SUV_mean
BSREM block-sequential regularized expectation maximization, OSEM ordered subsets expectation maximization, SNR signal-to-noise ratio