Table 1 Injected activity, dead time and dosimetry data for personalized and simulated empiric PRRT cycles (n = 564)
From: Impact of dead time on quantitative 177Lu-SPECT (QSPECT) and kidney dosimetry during PRRT
Minimum | 1st decile | Median | 9th decile | Maximum | |
|---|---|---|---|---|---|
Personalized PRRT (actual) | |||||
Injected activity (GBq) | 0.67 | 5.39 | 9.14 | 17.35 | 33.67 |
Dead time | |||||
Day 1 QSPECT (%) | 0.44 | 1.36 | 2.39 | 6.17 | 23.08 |
Day 3 QSPECT (%) | 0.28 | 0.73 | 1.36 | 3.83 | 22.14 |
Renal dosimetry | |||||
Absorbed dose (Gy) | 0.93 | 3.58 | 6.07 | 8.42 | 25.89 |
Absorbed dose per injected activity (Gy/GBq) | 0.14 | 0.34 | 0.63 | 1.11 | 4.93 |
Deviation without dead-time correction (%) | 2.82 | − 0.58 | − 1.39 | − 3.84 | − 22.14 |
Empiric PRRT (simulated, 7.4 GBq/cycle) | |||||
Dead time | |||||
Day 1 QSPECT (%) | 0.55 | 1.06 | 1.96 | 4.78 | 9.82 |
Day 3 QSPECT (%) | 0.28 | 0.55 | 1.15 | 3.08 | 7.21 |
Renal dosimetry | |||||
Absorbed dose (Gy) | 1.07 | 2.53 | 4.64 | 8.23 | 36.46 |
Deviation without dead-time correction (%) | 1.90 | − 0.54 | − 1.04 | − 2.60 | − 6.65 |