Table 4 Absorbed dose (Gy) to the nucleus of any cell of the 1 st and 2 nd neighbourhoods, for different distributions of 177Lu and 161Tb
From: Radiation doses from 161Tb and 177Lu in single tumour cells and micrometastases
Cell surface | Intracytoplasmic | Intranuclear | |||||
|---|---|---|---|---|---|---|---|
Neighbourhood | Neighbourhood | Neighbourhood | |||||
Cell position | 1 st | 2 nd | 1 st | 2 nd | 1 st | 2 nd | |
177Lu | Total dose in Gy | 6 | 4.7 | 7 | 5.8 | 14.6 | 13.5 |
Self-dose contribution | 32% | 40% | 43% | 52% | 74% | 80% | |
161Tb | Total dose in Gy | 12.4 | 9.8 | 15.3 | 12.9 | 45.2 | 43.1 |
Self-dose contribution | 40% | 51% | 54% | 65% | 85% | 90% | |