CT protocol optimisation in PET/CT: a systematic review

Bertolini, V.; Palmieri, A.; Bassi, M. C.; Bertolini, M.; Trojani, V.; Piccagli, V.; Fioroni, F.; Cavuto, S.; Guberti, M.; Versari, A.; Cola, S.

doi:10.1186/s40658-020-00287-x

EJNMMI Physics

Table 3 Eligible paediatric studies

From: CT protocol optimisation in PET/CT: a systematic review

Manufacturer	Number of articles	Number of datasets	Author	No. of pts	Protocol parameters												Dose index
Manufacturer	Number of articles	Number of datasets	Author	No. of pts	Scan type	Protocol intent	Scan district	X-Ray contrast use	kVp	mAs modulation	mA or mAs (reference)	Weight-based current selection	Rotation time (s)	Slice thickness (mm)	Pitch	Collimation	CTDI_vol (mGy)	ED (mSv)
GE Medical System	4	18	Sera et al. [11]	N.A.^c	axial	C	WB	N	120	N	80 mAs	N	1	N.A.	N	25	5.49	N.A.
			Sonoda, et al. [13]	100^b	helical	B	WB	N	140	N	80 mA	120 mA (if weight > 100 kg)	0.8	N.A.	1.5	4 × 2.5	N.A.	10.6 (± 2.2)
			Brady et al. [30]	N.A.^c		B	WB	N	80	Y	65–130 mA	between 0 and 9.4 Kg	N.A.	3.75	0.985	N.A.	N.A.	N.A.
				N.A.^c		B	WB	N	100	Y	80–160 mA	between 9.5 and 18.4 Kg	N.A.	3.75	0.985	N.A.	N.A.	N.A.
				N.A.^c		B	WB	N	100	Y	110–210 mA	between 18.5 and 31.4 Kg	N.A.	3.75	0.985	N.A.	N.A.	N.A.
				N.A.^c		B	WB	N	100	Y	110–220 mA	between 31.5 and 55 Kg	N.A.	3.75	0.985	N.A.	N.A.	N.A.
				N.A^c		B	WB	N	120	Y	150–210 mA	greater than 55 Kg	N.A.	3.75	0.985	N.A.	N.A.	N.A.
			Alessio et al. [31]	N.A.		A	WB	N	120	Y	10 mAs	between 6 and 7.4 Kg	0.5	2.5	0.98	N.A.	N.A.	3.1
				N.A.		A	WB	N	120	Y	10 mAs	between 7.5 and 9.4 Kg	0.5	2.5	0.98	N.A.	N.A.	2.9
				N.A.		A	WB	N	120	Y	15 mAs	between 9.5 and 11.4 Kg	0.5	2.5	0.98	N.A.	N.A.	4.1
				N.A.		A	WB	N	120	Y	20 mAs	between 11.5 and 14.4 Kg	0.5	2.5	0.98	N.A.	N.A.	5.2
				N.A.		A	WB	N	120	Y	20 mAs	between 14.5 and 18.4 Kg	0.5	2.5	0.98	N.A.	N.A.	5
				N.A.		A	WB	N	120	Y	20 mAs	between 18.5 and 22.4 Kg	0.5	2.5	0.98	N.A.	N.A.	4.7
				N.A.		A	WB	N	120	Y	25 mAs	between 22.5 and 31.4 Kg	0.5	2.5	0.98	N.A.	N.A.	5.5
				N.A.		A	WB	N	120	Y	30 mAs	between 31.5 and 40.5 Kg	0.5	2.5	0.98	N.A.	N.A.	6.3
				N.A.		A	WB	N	120	Y	30mAs	between 40.5 and 55 Kg	0.5	2.5	0.98	N.A.	N.A.	5.6
				N.A.		A	WB	N	120	Y	35 mAs	between 55 and 70 Kg	0.5	2.5	0.98	N.A.	N.A.	5.9
				N.A.		A	WB	N	120	Y	40 mAs	greater than 70 Kg	0.5	2.5	0.98	N.A.	N.A.	5.9
Philips Healthcare	1	2	–	–	axial	–	–	–	–	–	–	–	–	–	–	–	–	–
			Sera et al. [11]	N.A.^c	helical	C	WB	N	110	N.A.	50 mAs	N	0.6	N.A.	1.5	5	7.8	N.A.
			Sera et al. [11]	N.A.^c	helical	C	WB	N	130	N.A.	47 mAs	N	0.8	N.A.	0.8	3	5.54	N.A.
			–	–	N.A.	–	–	–	–	–	–	–	–	–	–	–	–	–
Siemens Healthcare	1	3	Sera et al. [11]	N.A.^c	axial	C	WB	N	120	N.A.	80 mAs	N	1	N.A.	N	10	7.34	N.A.
			Sera et al. [11]	N.A.^c	helical	C	WB	N	130	N.A.	50 mAs	N	0.8	N.A.	0.8	3	11.49	N.A.
			Sera et al. [11]	N.A.^c	helical	C	WB	N	130	N.A.	50 mAs	N	1	N.A.	0.55	3	10.92	N.A.
			–	–	N.A.	–	–	–	–	–	–	–	–	–	–	–	–	–

A CT acquisition for anatomic localization and attenuation correction, B CT acquisition for attenuation correction only (ultra-low dose), C CT acquisition for diagnostic purposes and attenuation correction, D WB CT acquisition for anatomic localization and attenuation correction + CT segmentary acquisition for diagnostic purpose, N.A. data not available, WB whole body, Y yes, N no, CTDI computed tomography dose index, ED effective dose
^bTotal not differentiated
^cClinical protocol studied on phantom, reported here with the same values both in paediatric and phantom tables

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