Phantom-based image quality assessment of clinical 18F-FDG protocols in digital PET/CT and comparison to conventional PMT-based PET/CT

EJNMMI Physics

Table 1 Systems, acquisition and reconstruction parameters applied in clinical whole-body oncologic ¹⁸F-FDG PET procedures

	Philips Vereos^d	Siemens Vision^d	Siemens mCT	GE Discovery-MI^d,a	GE Discovery 690
System parameters
Axial ring extent (mm)	164	261	221	250	153
Energy window (keV)	450–613	435–585	435–650	425–650	425–650
TOF’s resolution (ps)	316	215	540	370	544.3
NEMA System sensitivity (kcps/MBq)	5.6	16.4	9.6	22	7.5
Acquistion parameters
Acq. Time (min)	1.5	2	2.5	2.5	1.5
Admin. Activity (MBq/kg)	2	2	5	1.5	3.5
Acq. Time (min) × A admin. (TAP in min × MBq/kg)	3	4	12.5	3.75	5.25
Reconstruction parameters
Reconstruction methods	OSEM 3D TOF + PSF	OSEM 3D TOF + PSF	OSEM 3D TOF + PSF	OSEM 3D TOF + PSF	OSEM 3D TOF + PSF
Iterations and subsets (it,ss)	(3,15)/(2,10)	(4,5)	(3,21)	(3,16)	(3,16)
Filtre Gauss FWHM (mm)	0	0	3	6,4	5
Matrix size	144 × 144/288 × 288	440 × 440	512 × 512	256 × 256	256 × 256
Pixel size (mm)	4 × 4/2 × 2	1.65 × 1.65	1.59 × 1.59	2.73 × 2.73	2.73 × 2.73
Slice thickness (mm)	4/2	2	5	2.79	3.27

^aIn addition to OSEM, clinic FDG PET protocol for the GE Discovery MI also make use of the Q.Clear reconstruction algorithm (Q-param = 400)
^dDigital PET systems