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Table 4 Noise level of a large VOI (, 3.0 cm) placed in the liver and the SNR with all lesion sizes averaged are presenting for TOF-OSEM (3 iterations, 16 subsets, post-filter 5.0 mm and PSF) and BSREM with β = 750 (including TOF and PSF). Reference values measured in a healthy liver

From: Noise reduction using a Bayesian penalized-likelihood reconstruction algorithm on a time-of-flight PET-CT scanner

  Noise (14.137 ml) SNR (lesion size averaged)
Time (min)a OSEM β750 OSEM β750
2.5 0.443 0.228 20.256 41.710
5.0 0.318 0.156 15.088 29.092
10 0.217 0.109 10.243 19.448
  1. aTotal of nine range of times per bed position