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Fig. 4 | EJNMMI Physics

Fig. 4

From: Evaluation of a Bayesian penalized likelihood reconstruction algorithm for low-count clinical 18F-FDG PET/CT

Fig. 4

COV variation within the BPs. a.) Positioning of the NEMA phantom and the spheres within 2 BPs. Spheres are oriented such that they are the maximum of the sensitivity of a BP. b.) Region of interest (ROI) drawn in the NEMA phantom excluding the spheres used for background measurements of mean and SD values to calculate COV. c-d.) COV for different slices within 2 BPs and its overlap region with different acquisition times varying between 1 and 5 min/bed of the phantom filled at a 10-to-1 ratio (BG activity: 1.0 kBq/ml). Shown are the results of c.) OSEM+PSF reconstructions and d.) BPL 450 reconstructions. e.) Comparison of the COV for different slices at 1 min/bed and using an OSEM+PSF or BPL 450, 550 and 700 reconstructions. f.) Relation between the observed noise and the amount of counts detected per voxel based on PET sensitivity of the 11 central slices of a BP and known activity of the background. The first 5 points on the x-axis correspond to 1 to 5 min/bed. Two extra points were extracted from background measurements based on the 4-to-1 and 2-to-1 phantom measurements; BG activity: 1.7 kBq/ml and 2.6 kBq/ml, respectively

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