System evaluation of automated production and inhalation of 15O-labeled gaseous radiopharmaceuticals for the rapid 15O-oxygen PET examinations

EJNMMI Physics

Table 1 Radioactivity yields of C¹⁵O and ¹⁵O₂ gases and H₂¹⁵O saline for three different oxygen concentrations in nitrogen as the target gas

Oxygen concentration in nitrogen	C¹⁵O^a (MBq)	¹⁵O₂^a (MBq)	H₂¹⁵O^b (MBq)
0.3%	1757 ± 146*	2634 ± 145	731 ± 16
0.5%	1974 ± 39	2733 ± 60	735 ± 41
1.0%	2043 ± 69	2749 ± 72	742 ± 14

Note that H₂¹⁵O saline was produced by infusing saline over 60 s beginning 2 min after deuteron beam initiation. The sample volume of H₂¹⁵O saline was 10 mL
^aBeam intensity is 40 μA
^bBeam intensity is 10 μA