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Fig. 9 | EJNMMI Physics

Fig. 9

From: System evaluation of automated production and inhalation of 15O-labeled gaseous radiopharmaceuticals for the rapid 15O-oxygen PET examinations

Fig. 9

Example functional images of CBF, CMRO2, OEF, and vascular volume images of the arterial blood volume for H15O (V0W) and that for 15O2 (V0O), and CBV, obtained from a healthy volunteer of a 22-year-old male of the body weight 68 kg, with the net administration dose 503, 267, and 592  MBq corresponding to C15O, 15O2, and C15O2 inhalation, respectively. Functional images were calculated according to a modified DBFM [26] (a) and a DARG [25] (b) methods. Note that the functional images on both A and B were calculated from the same data acquired with the single PET scan during sequential inhalation of 15O2 and C15O2, but without C15O scan data on (a). CBV indicates high counts in the sinus area, while V0W does not show. V0O demonstrates significantly high counts. Of note is that image quality was reasonably well in both calculation methods, despite of gaseous radioactivity inhalation protocol

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