Table 1 Image error (mean ± standard deviation (minimum, maximum)) relative to CT attenuation correction of PET images reconstructed utilizing deepAC in various brain regions of 28 subjects and p values from paired t tests. p < 0.0024 is defined as the Bonferroni corrected significance level

− 1.04 ± 2.35 (− 6.67, 3.32)

2.43 ± 1.57 (0.65, 6.67)

0.18

− 1.15 ± 2.56 (− 6.61, 4.06)

2.59 ± 1.69 (0.82, 6.62)

0.15

− 0.79 ± 1.70 (− 4.45, 2.22)

2.11 ± 0.94 (1.07, 4.67)

0.18

− 0.73 ± 1.99 (− 4.77, 2.68)

2.32 ± 0.96 (1.10, 4.88)

0.055

− 1.70 ± 2.25 (− 5.56, 2.22)

2.52 ± 1.63 (0.51, 5.56)

0.01

− 1.92 ± 2.38 (− 5.60, 2.28)

2.79 ± 1.61 (0.69, 5.60)

0.005

− 1.78 ± 1.95 (− 6.24, 1.40)

2.38 ± 1.43 (0.69, 6.26)

0.01

− 1.92 ± 2.15 (− 6.12, 2.81)

2.75 ± 1.25 (0.89, 6.12)

0.004

− 0.22 ± 1.62 (− 3.86, 2.68)

1.70 ± 0.76 (0.67, 3.94)

0.154

− 0.27 ± 1.78 (− 3.79, 2.83)

1.78 ± 0.85 (0.54, 3.79)

0.146

0.69 ± 1.79 (− 3.20, 3.81)

1.77 ± 0.88 (0.74, 3.81)

0.354

0.37 ± 1.71 (− 3.38, 3.69)

1.50 ± 0.85 (0.43, 3.69)

0.613

0.32 ± 1.64 (− 3.47, 3.21)

1.33 ± 0.86 (0.33, 3.47)

0.451

− 0.67 ± 1.58 (− 3.80, 2.31)

1.41 ± 1.00 (0.24, 3.80)

0.115

− 0.74 ± 1.53 (− 3.94, 2.08)

1.40 ± 1.02 (0.27, 3.94)

0.009

− 0.07 ± 1.59 (− 3.90, 3.05)

1.40 ± 0.88 (0.31, 3.91)

0.172

0.00 ± 1.56 (− 4.04, 3.27)

1.34 ± 0.91 (0.20, 4.04)

0.283

− 0.39 ± 1.51 (− 3.71, 3.11)

1.25 ± 0.91 (0.12, 3.71)

0.056

− 0.56 ± 1.41 (− 3.83, 2.35)

1.24 ± 0.92 (0.29, 3.83)

0.013

− 0.50 ± 1.68 (− 4.02, 2.70)

1.61 ± 0.95 (0.35 4.02)

0.049

− 0.45 ± 1.63 (− 3.81, 2.28)

1.58 ± 0.87 (0.35, 3.81)

0.057

− 0.64 ± 1.99 (− 4.18, 2.22)

1.74 ± 0.94 (0.29, 4.20)