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Table 7 Correlation between body size predictors, eGFR, and the IA per renal absorbed dose (GBq/Gy) at the first induction cycle (n = 77)

From: Accuracy and reproducibility of simplified QSPECT dosimetry for personalized 177Lu-octreotate PRRT

 

Correlation a

Linear regression slope

Relative error (%)

3TP

2TP

3TP

2TP

3TP

2TP

r

P

r

P

Weight (Kg)

0.13

0.25

0.13

0.26

0.026

0.026

2.3

[−46.0–66.6]

(− 61.5–165.7)

2.0

[−47.0–66.3]

(− 62.6–168.8)

LBW (Kg)

0.18

0.12

0.17

0.13

0.037

0.036

5.6

[−38.4–73.9]

(− 58.4–190.4)

6.8

[− 39.4–71.0]

(− 59.6–193.7)

BSA (m2)

0.16

0.17

0.15

0.13

1.09

1.07

7.4

[−38.2–73.5]

(− 53.5–227.7)

6.9

[− 39.1–76.8]

(− 54.8–231.5)

eGFR (ml/min/1.73m2)

0.34

0.002

0.36

0.001

0.022

0.021

1.0

[− 36.2–70.2]

(− 61.2–164.1)

1.5

[− 36.2–71.9]

(− 61.1–173.3)

eGFR · weight

0.34

0.002

0.35

0.002

0.00026

0.00026

−1.9

[− 46.7–63.8]

(− 62.9–124.4)

−2.7

[− 45.9–61.7]

(− 62.8–123.3)

eGFR · LBW

0.40

0.0003

0.41

0.0002

0.00037

0.00036

−0.3

[− 43.0–57.1]

(− 67.6–140.2)

0.8

[− 43.4–58.3]

(− 67.5–139.0)

eGFR · BSA

0.38

0.0008

0.39

0.0005

0.012

0.012

− 0.0

[−36.2–70.2]

(− 63.8–128.2)

− 0.7

[− 36.9–70.1]

(− 63.7–127.3)

  1. BSA body surface area, eGFR estimated glomerular filtration rate, LBW lean body weight, TP time points
  2. Relative error data is presented as median [interdecile range] (range)
  3. aSpearman’s correlation