Table 4 Per-cycle dosimetry estimates obtained with hybrid methods based on two time points for the first cycle and one time point or no imaging at all for subsequent cycles (induction cycles only, n = 173)

Kidney

4.8

[2.9–6.6]

(1.6–8.7)

5.1

[3.0–7.1]

(1.8–11.3)

4.9

[3.0–6.9]

(1.7–9.2)

4.7

[2.7–7.3]

(1.1–10.5)

3.4

[− 9.5–26.8]

(− 38.3–86.3)

2.2

[− 2.0–7.4]

(− 17.9–32.1)

0.6

[− 23.5–27.8]

(− 60.2–106.3)

Bone marrow_self

0.29

[0.14–0.65]

(0.06–3.84)

0.22

[0.11–0.73]

(0.06–2.33)

0.24

[0.13–0.64]

(0.06–2.83)

0.24

[0.10–0.65]

(0.04–3.85)

−7.0

[− 56.6–76.3]

(− 73.9–155.8)

−7.2

[− 33.2–22.4]

(− 44.2–51.0)

−13.8

[− 56.0–65.3]

(− 93.8–370.9)

Bone marrow_cross

0.023

[0.011–0.052]

(0.005–0.100)

0.022

[0.011–0.054]

(0.003–0.113)

0.021

[0.010–0.050]

(0.004–0.107)

0.022

[0.010–0.060]

(0.003–0.141)

−2.2

[− 21.2–14.9]

(− 55.1–66.4)

−4.2

[− 15.7–2.7]

(− 37.3–22.6)

1.3

[− 35.7–40.8]

(− 52.5–113.0)

Tumor_max^b

29.7

[6.2–65.9]

(1.7–120.0)

32.8

[7.0–66.6]

(1.5–104.5)

31.2

[6.2–66.8]

(1.9–102.1)

45.6

[9.9–113.9]

(3.2–235.1)

3.6

[− 20.4–39.0]

(− 46.7–141.8)

2.3

[− 11.5–21.6]

(− 30.2–65.3)

31.0

[− 13.0–192.5]

(− 49.9–6171.7)