Fig. 2 (abstract A24).
18F and 124I TOF histo-images, obtained by backprojection of attenuation-corrected histo-projections. The three image rows from top to bottom correspond to simulated 2.5-minute simultaneous acquisitions of both tracers using, respectively, 1, 2, and 3 axial PennPET Explorer detector rings, showing progressively reduced image noise for the longer PET systems. The 124I images in the right-hand column were made solely from triple-coincidence events. The 124I histo-projections were scaled, using the known efficiencies for double- and triple-coincidence events, and then subtracted from the total double-coincidence histo-projections to estimate the TOF data for 18F alone. The resulting 18F histo-images are shown in the left-hand column. These separated histo-images will be used to initialize a simultaneous joint reconstruction of both tracer distributions from all recorded double- and triple-coincidence events using OSEM