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Table 2 Summary of acquisition and processing parameters used. See text for full details

From: Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals

 

Site

1

2

3

4

5

6

7

Camera

Siemens Symbia T2

Siemens Symbia T2

GE Infinia Hawkeye 4

Siemens Intevo

Ge Optima 640

Siemens Symbia T6

GE Discovery 670

Collimator

ME

ME

MEGP

ME

MEGP

MELP

MEGP

Crystal thickness

5/8″

3/8″

3/8″

3/8″

3/8″

3/8″

5/8″

Photopeak(s), keV

113 ± 7.5%

113 ± 10%

113 ± 10%

208 ± 10%

208 ± 10%

208 ± 10%

208 ± 10%

208 ± 10%

208 ± 10%

208 ± 10%

Scatter window(s), keV

98.7 ± 5%

131 ± 5%

176.8 ± 5%

178 ± 5%

178 ± 5%

239.2 ± 5%

214 ± 5%

214 ± 5%

Orbit type

Contoured

Circular

Contoured

Contoured

Contoured

Circular

Contoured

Matrix

128 × 128

128 × 128

128 × 128

128 × 128

128 × 128

128 × 128

128 × 128

Number of projections

120

120

120

120

120

120

120

Time per projection

30 s

30 s

30 s

30 s

30 s

30 s

60 s *

Reconstruction type

OSEM

OSEM

OSEM

OSEM

OSEM

OSEM

OSEM

Iterations/subsets

6/6

8/4

16/5

24/24

5/10

5/15

8/10

Attenuation correction

CT

CT

CT

CT

CT

CT

CT

Scatter correction

TEW

No

Monte Carlo

TEW

TEW

Monte Carlo

ESSE

Resolution recovery

Yes

No

Yes

Yes

No

Yes

Yes

Segmentation method

CT VOI + 10 mm

SPECT threshold

CT VOI

CT VOI

CT VOI

CT VOI

CT VOI plus SPECT auto-threshold

  1. *The activity of the source used at site H7 was approximately 50% of that used in all other sites, so the acquisition time was doubled to compensate for this