Fig. 5
From: Feasibility of simplifying renal dosimetry in 177Lu peptide receptor radionuclide therapy
a, b Renal time-activity data (for the left and right kidneys, respectively) for 80 patients and all treatment cycles (in total approximately 300 curves), where curves have been normalized to a value of 100 at the second imaging time point (24 h). Red symbols are data acquired at one centre (39 patients), with nominal times of 1, 24, 48 and 168 h. Green symbols are acquired at the other centre (40 patients), with nominal times of 1, 24, 96 and 168 h. Grey lines are the fitted time-activity curves, also normalized to 100 at the time of the second imaging time point for each individual dataset. c Estimated effective half-times for the left and right kidneys after the second imaging time point. d The fractional absorbed dose that is due to activity retention after second imaging time point, determined as the absorbed dose delivered from 24 h and onwards, divided by the totally delivered absorbed dose