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Table 2 Values of SUVs (corrected for bw, lbm, and bsa) of a single lesion, large enough to be selected as target lesion per RECIST, and a whole body total glycolytic activity for tumor burden for two different reconstructions (site standard of care PSF and EARL)

From: Guidelines for quality control of PET/CT scans in a multicenter clinical study

  body weight-corrected SUV lbm-corrected SUV bsa-corrected SUV
Statistic ROI-1 ROI-1 ROI-1 bw (above 40%) ROI-1 bw (above 40%) Whole body (above 2.5 SUVbw) Whole body (above 2.5 SUVbw) ROI-1 ROI-1 ROI-1 (above 40% SUVlbm) ROI-1 (above 40.% SUVlbm) Whole body (above 2.5 SUVlbm) Whole body (above 2.5 SUVlbm) ROI-1 ROI-1 ROI-1 (above 40% SUVbsa) ROI-1 (above 40.% SUVbsa) Whole body (above 2.5 SUVbsa) Whole body (above 2.5 SUVbsa)
Reconstruction PSF EARL PSF EARL PSF EARL PSF EARL PSF EARL PSF EARL PSF EARL PSF EARL PSF EARL
Max (SUV) value 17.34 12.26 17.34 12.26 18.04 13.07 14.08 9.95 14.08 9.95 14.64 10.61 0.44 0.31 0.44 0.31 0.46 0.33
% change 41.47 38.04 41.47 38.04 41.47 38.04
Mean (SUV) value 5.94 5.16 11.11 7.65 5.24 4.78 4.82 4.19 9.02 6.21 4.26 3.88 0.15 0.13 0.28 0.19 0.13 0.12
% change 15.14 9.58 15.14 9.58 15.14 9.58
PERCIST SUV peak 12.21 9.29 9.91 7.54 0.31 0.24
% change 31.37 31.37 31.37
Total glycolytic activity (SUV*ml) value 44.83 38.93 25.61 25.44 1329.13 1212.89 36.38 31.6 20.78 20.65 1078.75 984.41 1.14 0.99 0.65 0.65 33.77 30.82
% change 15.14 9.58 15.14 9.58 15.14 9.58
Volume (ml) value 7.54 7.54 2.3 3.33 253.49 253.49 7.54 7.54 2.3 3.33 253.49 253.49 7.54 7.54 2.3 3.33 253.49 253.49