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Fig. 8 | EJNMMI Physics

Fig. 8

From: Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation

Fig. 8

Visual agreement according to ManRegMI coregistration. Overview of axial layers (every 4 mm) throughout the prostate volume for patients 1 (top), 2 (middle), and 3 (bottom) for the ManRegMI coregistration. The images in each row are ordered from apex (left) to basis (right). For each patient, PSMA-PET and histoPET are presented separately from each other, with CT overlay for better orientation. The last row in each image shows the direct comparison of PSMA-PET and histoPET. Note that some discrepancies between PSMA-PET and histoPET, such as the pronounced PSMA-PET signal at the dorsal and cranial prostate region for patient 2 (middle image), may be due to missing histopathologic information. Such regions were excluded from the further quantitative analysis in order not to bias the results

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