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Fig. 5 | EJNMMI Physics

Fig. 5

From: Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation

Fig. 5

Visual comparison of PSMA-PET/CT and histoPET models according to DefReg and DefRegMI coregistration. The deformation of the 3D histoPET by the deformable registration algorithm is clearly visible. Results showed that DefReg is more sensitive to uncertainties in contours of the prostate on in vivo and ex vivo CT than the pure manual ManReg is. However, pattern agreement between PSMA-PET and histoPET with R 2 values from 50.8 to 62.2% without and with MI coregistration step were achieved

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