Skip to main content

Table 2 VOI size (cm3) and model preference (%) for [18F]HX4 kinetics in various tissues according to AIC, based on the 2.5 h dynamic PET data

From: Pharmacokinetic modeling of a novel hypoxia PET tracer [18F]HX4 in patients with non-small cell lung cancer

  

Model

Tissue type

VOI size (cm3)

1T2k

2T3k

2T4k

1T2k+VB

2T3k+VB

2T4k+VB

Fat

3.7 ± 1.1

25

12.5

50

12.5

Lung

20.1 ± 9.3

37.5

50

12.5

Muscle

4.5 ± 2.5

12.5

25

62.5

Liver

17.1 ± 9.2

25

75

Tumor

111.4 ± 64.1

100

Tumor, viable

48.0 ± 27.2

100

Tumor, high

3.0 ± 2.8

25

12.5

62.5

Tumor, mid

1.8 ± 0.8

12.5

25

37.5

25

Tumor, low

1.1 ± 0.2

75

25

  1. For clarity, values of 0% are not shown