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Table 3 Clinically representative 177Lu MRT absorbed dose calculation using calibration factors from 3D printed organ inserts and spherical and cylindrical inserts

From: Organ-specific SPECT activity calibration using 3D printed phantoms for molecular radiotherapy dosimetry

 

Organ factor

Sphere factor a

Cylinder factor b

 

A cumulative

Abs. Dose

A cumulative

Abs. dose

Δ Dose c

A cumulative

Abs. dose

Δ Dose c

 

(GBq.Hrs)

(mGy)

(GBq.Hrs)

(mGy)

(%)

(GBq.Hrs)

(mGy)

(%)

Spleen

48.8 ± 9.2

10500

54.9 ± 10.1

11800

11.0

43.4 ± 0.8

9370

−12.1

Liver

59.8 ± 4.2

2690

78.6 ± 5.5

3540

24.0

62.1 ± 4.4

2790

3.6

Kidneys

13.9 ± 1.6

6040

15.0 ± 1.1

6570

8.1

11.9 ± 0.8

5190

−16.4

  1. OLINDA/EXM calculations [2] using representative organ-specific time-activity curve data from clinical patient
  2. a113-ml volume
  3. b278-ml volume
  4. cChanged in absorbed dose compared to using organ calibration factor