Table 2 \( {\mathrm{EC}}_{50}^{\mathrm{drug},\mathrm{D}3} \) and \( {\mathrm{EC}}_{50}^{\mathrm{drug},\mathrm{D}2} \) for GSK618334 estimated before and after motion correction (MC)
MC Method | Removal of unrealistic BPND data points | \( {\mathrm{EC}}_{50}^{\mathrm{drug},\mathrm{D}3} \) of GSK618334 (ng/ml) | \( {\mathrm{EC}}_{50}^{\mathrm{drug},\mathrm{D}2} \) of GSK618334 (ng/ml) |
|---|---|---|---|
No MC | Required | 15 (−6, 37) | 529 (206, 852) |
MC by FBF | Required | 4 (0, 8) | 492 (327, 658) |
MC by GIR | Not necessary | 10 (5, 15) | 539 (419, 660) |