A novel phantom technique for evaluating the performance of PET auto-segmentation methods in delineating heterogeneous and irregular lesions

EJNMMI Physics

Table 4 S and PPV obtained by the PET-AS methods for the spheroidal and irregular H&N lesion for different uptake patterns (cf. Fig. 7)

	Homogeneous		Gaussian		Two-level		Necrotic		Necrotic Gaussian
	S	PPV	S	PPV	S	PPV	S	PPV	S	PPV
	Spheroids
AT	0.845	1.000	0.852	0.939	N/A	N/A	0.814	0.626	0.922	0.696
RG	0.891	0.889	0.892	0.893	N/A	N/A	0.998	0.473	1.000	0.518
GCM2	0.795	1.000	0.791	1.000	N/A	N/A	0.924	0.635	0.983	0.673
GCM3	0.854	0.996	0.817	0.940	N/A	N/A	0.956	0.605	0.998	0.645
GCM4	0.952	0.745	0.911	0.873	N/A	N/A	0.996	0.416	1.000	0.455
GCM5	0.979	0.539	0.975	0.713	N/A	N/A	1.000	0.261	1.000	0.306
GCM6	0.998	0.378	0.992	0.605	N/A	N/A	1.000	0.179	1.000	0.200
WT	0.962	0.773	0.954	0.780	N/A	N/A	0.956	0.440	0.979	0.539
	Irregular lesions
AT	0.963	0.751	0.755	0.843	0.961	0.632	0.969	0.670	1.000	0.608
RG	0.994	0.645	0.810	0.742	0.993	0.581	1.000	0.543	1.000	0.533
GCM2	1.000	0.423	0.982	0.472	0.954	0.659	1.000	0.389	1.000	0.395
GCM3	0.976	0.768	0.767	0.828	0.934	0.721	0.994	0.616	1.000	0.608
GCM4	1.000	0.538	0.896	0.629	0.980	0.558	1.000	0.421	1.000	0.420
GCM5	1.000	0.362	0.976	0.497	0.993	0.470	1.000	0.270	1.000	0.287
GCM6	1.000	0.242	1.000	0.348	1.000	0.403	1.000	0.185	1.000	0.203
WT	0.988	0.495	0.865	0.571	1.000	0.420	1.000	0.419	0.994	0.433