Intravenous contrast-enhanced CT can be used for CT-based attenuation correction in clinical 111In-octreotide SPECT/CT

EJNMMI Physics

Table 3 Image score quality for the 10 patients showed significant difference ( p < 0.04) between FDAP and FDVP only

Patient #	Image score			Lesion value (max pixel)			Krenning score	Lesion location
	LD	FDAP	FDVP	LD	FDAP	FDVP	LD, FDAP, FDVP
1	4	4	5	498	516	446	4, 4, 4	Liver
				135	145	146	3, 3, 3	Lymph Node
2	4	3	4	678	671	661	4, 4, 4	Liver
3	4	3	4	49	46	55	3, 3, 3	Liver
				158	171	174	3, 3, 3	Lymph Node
4	4	4	4	753	813	790	4, 4, 4	Lymph Node
5	4	4	4	270	320	309	3, 3, 3	Pancreas
6	5	4	4	142	162	168	3, 3, 3	Lymph Node
7	4	4	5	65	67	68	3, 3, 3	Liver
				543	593	593	4, 4, 4	Lymph Node
8	4	4	4	249	295	290	3, 4, 4	Liver
				186	186	192	3, 3, 4	Bone
9	4	4	4	131	133	130	3, 3, 3	Liver
				358	385	385	3, 4, 4	Lymph Node
10	4	4	4	382	410	423	4, 4, 4	Liver
				89	83	81	3, 3, 3	Lymph Node
Average	4.1 ± 0.3	3.8 ± 0.4	4.2 ± 0.4	293 ± 214	312 ± 226	307 ± 218	4.1, 3.8, 4.2	N/A

Max pixel values for the 16 lesions shows significantly lower values for LD than for FD; p < 0.003 and p < 0.05 for arterial and venous phase, respectively. On the average, LD values are 6% ± 7% and 6% ± 8% lower. For 13 out of 16 lesions, the Krenning score is identical in all the CT phases. In the remaining three lesions (highlighted), the Krenning score differed by no more than one.