Impact of point spread function modelling and time of flight on FDG uptake measurements in lung lesions using alternative filtering strategies

EJNMMI Physics

Table 5 Relative uptake differences for matched SUV _max recovery

Uptake		TOF	HD	UHD
SUV_max	Mean% change	+5.4%	+0.6%	+5.3%
	95% CI	−8.5% to +19%	−8.1% to +9.4%	−9.5% to +20%
	n > 25% change	1/74	0/74	2/74
SUV_peak	Mean% change	+5.3%	+1.7%	+6.3%
	95% CI	−6.4% to +17%	−3.0% to +6.5%	−4.9% to +17%
	n > 30% change	0/74	0/74	1/74
TLG-40	Mean% change	+3.8%	+2.4%	+4.0%
	95% CI	−13% to +20%	−13% to +18%	−12% to +20%

Mean percentage changes and 95% confidence intervals of the three uptake measures relative to OSEM reconstruction. Also shown are the number of lesions with a greater than 25% and 30% increase in SUV_max and SUV_peak, respectively. Data in the table are from images using post-filters to match SUV_max.