Example static FDG PET acquisitions processed with data driven gating and signal optimization. (A) Whole body FDG PET scan. (B) FDG PET scan attenuation corrected with (PET-) driven gated CT. Top row: vendor reconstruction of non-gated acquisition. Middle row: gated image derived from data-driven gating applied to non-gated acquisition. Bottom row: optimized gated image created through signal optimization procedure applied to the gated images derived from data-driven gating. See Additional files 1 and 2 for cine loop illustrating the motion information captured in the gated and optimized gated images.