Figure 3

A prostate cancer patient with¹¹ C-choline injection. (a) The original fused PET/CT image, with no simulated lesion (the ‘true’ original large tumor is visible in the prostate); (b) the OSEM reconstruction with the same parameters as in the original image (5.5 × 5.5 × 3.3 mm³ voxels, OSEM with 20 subsets, 2 iterations, and a 6-mm post-reconstruction filter), after insertion of two 6 mm lesions with SUV = 8; (c) the PSF + TOF reconstruction with 2-mm voxel size and 4-mm filter, after insertion of the two 6-mm lesions. The arrows point to the location of the simulated lesions.