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  1. Original research

    Technical note: how to determine the FDG activity for tumour PET imaging that satisfies European guidelines

    For tumour imaging with PET, the literature proposes to administer a patient-specific FDG activity that depends quadratically on a patient’s body weight. However, a practical approach on how to implement such ...

    Daniëlle Koopman, Jochen A. C. van Osch, Pieter L. Jager, Carlijn J. A. Tenbergen, Siert Knollema, Cornelis H. Slump and Jorn A. van Dalen

    EJNMMI Physics 2016 3:22

    Published on: 29 September 2016

  2. Original research

    A novel planar image-based method for bone marrow dosimetry in 177Lu-DOTATATE treatment correlates with haematological toxicity

    177Lu-DOTATATE is a valuable treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. Though well tolerated in general, bone marrow to...

    Johanna Svensson, Tobias Rydén, Linn Hagmarker, Jens Hemmingsson, Bo Wängberg and Peter Bernhardt

    EJNMMI Physics 2016 3:21

    Published on: 22 September 2016

  3. Original research

    Multimodality calibration for simultaneous fluoroscopic and nuclear imaging

    Simultaneous real-time fluoroscopic and nuclear imaging could benefit image-guided (oncological) procedures. To this end, a hybrid modality is currently being developed by our group, by combining a c-arm with ...

    Casper Beijst, Mattijs Elschot, Sandra van der Velden and Hugo W. A. M. de Jong

    EJNMMI Physics 2016 3:20

    Published on: 30 August 2016

  4. Review

    An overview of CEST MRI for non-MR physicists

    The search for novel image contrasts has been a major driving force in the magnetic resonance (MR) research community, in order to gain further information on the body’s physiological and pathological conditions.

    B. Wu, G. Warnock, M. Zaiss, C. Lin, M. Chen, Z. Zhou, L. Mu, D. Nanz, R. Tuura and G. Delso

    EJNMMI Physics 2016 3:19

    Published on: 26 August 2016

  5. Short communication

    A robust conversion method of radioactivities between plastic and NaI scintillation well counters for long-term quality control and quality assurance

    The purpose of this study is to specify a simple procedure for a robust data conversion of radioactivity value between plastic scintillator (PL) and NaI scintillator (NaI) devices.

    Takeshi Hara, Tadahiko Ishihara, Takahiko Asano, Masayuki Matsuo, Tetsuro Katafuchi and Hiroshi Fujita

    EJNMMI Physics 2016 3:18

    Published on: 15 August 2016

  6. Original research

    Radiation exposure of the spleen during 177Lu-DOTATATE treatment and its correlation with haematological toxicity and spleen volume

    Somatostatin analogue-based radionuclide therapy with 177Lu-DOTATATE is an important treatment option for patients with advanced neuroendocrine tumours overexpressing somatostatin receptors. In addition to the ki...

    Johanna Svensson, Linn Hagmarker, Tobias Magnander, Bo Wängberg and Peter Bernhardt

    EJNMMI Physics 2016 3:15

    Published on: 5 August 2016

  7. Original research

    Effect of dosimeter’s position on occupational radiation extremity dose measurement for nuclear medicine workers during 18F-FDG preparation for PET/CT

    The recent spread of positron emission tomography-computed tomography (PET/CT) poses extremity dosimetry challenges. The question arose whether the radiation dose measured by the ring thermoluminescent dosimet...

    Fabien Salesses, Paul Perez, Aline E. Maillard, Julie Blanchard, Sabine Mallard and Laurence Bordenave

    EJNMMI Physics 2016 3:16

    Published on: 5 August 2016

  8. Original research

    Abdo-Man: a 3D-printed anthropomorphic phantom for validating quantitative SIRT

    The use of selective internal radiation therapy (SIRT) is rapidly increasing, and the need for quantification and dosimetry is becoming more widespread to facilitate treatment planning and verification. The ai...

    Jonathan I. Gear, Craig Cummings, Allison J. Craig, Antigoni Divoli, Clive D. C. Long, Michael Tapner and Glenn D. Flux

    EJNMMI Physics 2016 3:17

    Published on: 5 August 2016

  9. Original research

    A study of SPECT/CT camera stability for quantitative imaging

    The purpose of this study was twofold: to evaluate the quantitative stability of a SPECT/CT gamma camera over time and to determine if daily flood acquisitions can reliably serve as calibration factors for qua...

    Wendy A. McDougald, Robert S. Miyaoka, Adam M. Alessio, Robert L. Harrison and Thomas K. Lewellen

    EJNMMI Physics 2016 3:14

    Published on: 29 July 2016

  10. Original Research

    Organ-specific SPECT activity calibration using 3D printed phantoms for molecular radiotherapy dosimetry

    Patient-specific absorbed dose calculations for molecular radiotherapy require accurate activity quantification. This is commonly derived from Single-Photon Emission Computed Tomography (SPECT) imaging using a...

    Andrew P. Robinson, Jill Tipping, David M. Cullen, David Hamilton, Richard Brown, Alex Flynn, Christopher Oldfield, Emma Page, Emlyn Price, Andrew Smith and Richard Snee

    EJNMMI Physics 2016 3:12

    Published on: 13 July 2016

  11. Original research

    Simultaneous Tc-99m and I-123 dual-radionuclide imaging with a solid-state detector-based brain-SPECT system and energy-based scatter correction

    A brain single-photon emission computed tomography (SPECT) system using cadmium telluride (CdTe) solid-state detectors was previously developed. This CdTe-SPECT system is suitable for simultaneous dual-radionu...

    Wataru Takeuchi, Atsuro Suzuki, Tohru Shiga, Naoki Kubo, Yuichi Morimoto, Yuichiro Ueno, Keiji Kobashi, Kikuo Umegaki and Nagara Tamaki

    EJNMMI Physics 2016 3:10

    Published on: 29 June 2016

  12. Original Research

    Lesion quantification and detection in myocardial 18F-FDG PET using edge-preserving priors and anatomical information from CT and MRI: a simulation study

    The limited spatial resolution of the clinical PET scanners results in image blurring and does not allow for accurate quantification of very thin or small structures (known as partial volume effect). In cardiac i...

    Anna Turco, Johan Nuyts, Olivier Gheysens, Jürgen Duchenne, Jens-Uwe Voigt, Piet Claus and Kathleen Vunckx

    EJNMMI Physics 2016 3:9

    Published on: 17 June 2016

  13. Original research

    Simultaneous PET/MRI with 13C magnetic resonance spectroscopic imaging (hyperPET): phantom-based evaluation of PET quantification

    Integrated PET/MRI with hyperpolarized 13C magnetic resonance spectroscopic imaging (13C-MRSI) offers simultaneous, dual-modality metabolic imaging. A prerequisite for the use of simultaneous imaging is the absen...

    Adam E. Hansen, Flemming L. Andersen, Sarah T. Henriksen, Alexandre Vignaud, Jan H. Ardenkjaer-Larsen, Liselotte Højgaard, Andreas Kjaer and Thomas L. Klausen

    EJNMMI Physics 2016 3:7

    Published on: 22 April 2016

  14. Original research

    Optimization of brain PET imaging for a multicentre trial: the French CATI experience

    CATI is a French initiative launched in 2010 to handle the neuroimaging of a large cohort of subjects recruited for an Alzheimer’s research program called MEMENTO. This paper presents our test protocol and res...

    Marie-Odile Habert, Sullivan Marie, Hugo Bertin, Moana Reynal, Jean-Baptiste Martini, Mamadou Diallo, Aurélie Kas and Régine Trébossen

    EJNMMI Physics 2016 3:6

    Published on: 5 April 2016

  15. Original research

    Quantitative comparison of PET performance—Siemens Biograph mCT and mMR

    Integrated clinical whole-body PET/MR systems were introduced in 2010. In order to bring this technology into clinical usage, it is of great importance to compare the performance with the well-established PET/...

    Anna M. Karlberg, Oddbjørn Sæther, Live Eikenes and Pål Erik Goa

    EJNMMI Physics 2016 3:5

    Published on: 25 February 2016

  16. Review

    Recent developments in time-of-flight PET

    While the first time-of-flight (TOF)-positron emission tomography (PET) systems were already built in the early 1980s, limited clinical studies were acquired on these scanners. PET was still a research tool, a...

    S. Vandenberghe, E. Mikhaylova, E. D’Hoe, P. Mollet and J. S. Karp

    EJNMMI Physics 2016 3:3

    Published on: 16 February 2016

  17. Original research

    CADA—computer-aided DaTSCAN analysis

    Dopamine transporter (DaT) imaging (DaTSCAN) is useful for the differential diagnosis of parkinsonian syndromes. Visual evaluation of DaTSCAN images represents the generally accepted diagnostic method, but it ...

    Antonio Augimeri, Andrea Cherubini, Giuseppe Lucio Cascini, Domenico Galea, Maria Eugenia Caligiuri, Gaetano Barbagallo, Gennarina Arabia and Aldo Quattrone

    EJNMMI Physics 2016 3:4

    Published on: 16 February 2016

  18. Original Research

    Fully automated calculation of image-derived input function in simultaneous PET/MRI in a sheep model

    Obtaining the arterial input function (AIF) from image data in dynamic positron emission tomography (PET) examinations is a non-invasive alternative to arterial blood sampling. In simultaneous PET/magnetic res...

    Thies H. Jochimsen, Vilia Zeisig, Jessica Schulz, Peter Werner, Marianne Patt, Jörg Patt, Antje Y. Dreyer, Johannes Boltze, Henryk Barthel, Osama Sabri and Bernhard Sattler

    EJNMMI Physics 2016 3:2

    Published on: 13 February 2016

  19. Original research

    A novel statistical analysis method to improve the detection of hepatic foci of 111In-octreotide in SPECT/CT imaging

    Low uptake ratios, high noise, poor resolution, and low contrast all combine to make the detection of neuroendocrine liver tumours by 111In-octreotide single photon emission tomography (SPECT) imaging a challenge...

    Tobias Magnander, E. Wikberg, J. Svensson, P. Gjertsson, B. Wängberg, M. Båth and Peter Bernhardt

    EJNMMI Physics 2016 3:1

    Published on: 19 January 2016

  20. Original research

    Cyclotron production of 43Sc for PET imaging

    Recently, significant interest in 44Sc as a tracer for positron emission tomography (PET) imaging has been observed. Unfortunately, the co-emission by 44Sc of high-energy γ rays (E γ = ...

    Rafał Walczak, Seweryn Krajewski, Katarzyna Szkliniarz, Mateusz Sitarz, Kamel Abbas, Jarosław Choiński, Andrzej Jakubowski, Jerzy Jastrzębski, Agnieszka Majkowska, Federica Simonelli, Anna Stolarz, Agnieszka Trzcińska, Wiktor Zipper and Aleksander Bilewicz

    EJNMMI Physics 2015 2:33

    Published on: 4 December 2015

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