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Table 1 Patient characteristics

From: Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model

Characteristic

Median (range)

Patients (n)

76

Age (years)

73 (48–91)

Weight (kg)

79 (61–116)

GFR (calculated using Cockcroft Gault) (mL/min)

80.9 (25.9–181)

Hematocrit

0.35 (0.22–0.44)

Baseline PSA (µg/L)

260 (0.12–4896)

Tumor volume of segmented tumors (L)

0.0443 (0.000122–0.546)

Injected radioactivity (MBq)

7378 (5605–7763)

Received dosing schedule (n)

 

 ‘4 × 6’

10

 ‘2 × 2—repeated after twelve weeks’

66

Number of cycles received (n)

 

 1

76

 2

74

 3

48

 4

37

 5

6

 6

4

 7

1

 8

1

  1. GFR glomerular filtration rate, PSA prostate-specific antigen