Fig. 3

Box plots of liver noise (A), lesion SNR (B), lesion SBR (C) and lesion SUVmax comparison between 0% simulated activity reduction with factor β = 300 and 17%, 33%, 50% and 67% simulated activity reductions reconstructed with different values of factor β (150, 300, 450 and 600). Box plots of simulated activity reductions with equal or improved values compared to 0% simulated activity reduction with factor β = 300 (red) are displayed in black. The central line of the box plot represents the median value. The whiskers extent to the minimum and maximum values or 1.5 interquartile range (IQR) of the lower and the upper quartiles. Values outside the 1.5 IQR are plotted. Significant differences (p ≤ 0.05) compared to 0% simulated activity reduction with factor β = 300 determined by Friedman test with additional Dunn’s multiple comparisons test are indicated with asterisks