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Table 3 Kinetic parameters estimated with the 4C model and 3C model

From: Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model

Model

Parameters

HCC

Liver tissue

AUC

P

4C

K1

1.441 ± 0.314

1.179 ± 0.465

0.636

0.019

k2

1.018 ± 0.448

0.704 ± 0.491

0.698

0.020

k3

1.348 ± 0.216

1.103 ± 0.509

0.629

0.022

k5

0.978 ± 0.490

1.372 ± 0.506

0.734

0.006

k6

0.037 ± 0.050

0.038 ± 0.053

0.599

0.956

HPI (%)

0.836 ± 0.237

0.254 ± 0.286

0.916

< 0.001

Vb

0.075 ± 0.133

0.029 ± 0.058

0.636

0.127

Vi

0.540 ± 0.399

0.286 ± 0.430

0.622

0.032

v

0.317 ± 0.438

0.063 ± 0.215

0.668

0.013

All*

  

0.931

 

3C

K1

1.302 ± 0.294

1.235 ± 0.418

0.541

0.498

k2

1.435 ± 0.298

1.260 ± 0.406

0.607

0.080

k3

0.047 ± 0.055

0.017 ± 0.030

0.719

0.021

k4

0.026 ± 0.040

0.041 ± 0.053

0.552

0.239

HPI (%)

0.652 ± 0.328

0.207 ± 0.211

0.864

< 0.001

Vb

0.208 ± 0.176

0.043 ± 0.062

0.875

< 0.001

All*

  

0.892

 

SUVmax

5.131 ± 2.776

2.791 ± 0.711

0.814

< 0.001

  1. Bold values indicate significant differences in this parameter
  2. *The multiparametric ROC