Table 3 Mean (± SD) organ-specific time-integrated activity coefficients (TIAC) for 124I-mIBG in adult patients and their extrapolation to reference paediatric patients defined in ICRP89
Organ | TIAC (h) | ||||||
|---|---|---|---|---|---|---|---|
Adult Male | Adult Female | 15-yrs-old | 10-yrs-old | 5-yrs-old | 1-yr-old | Newborn | |
Salivary glands | 0.41 (0.15) | 0.42 (0.17) | 0.44 (0.17) | 0.49 (0.19) | 0.64 (0.25) | 0.86 (0.34) | 0.62 (0.24) |
Heart wall | 0.86 (0.42) | 0.93 (0.22) | 0.85 (0.30) | 0.90 (0.32) | 0.92 (0.32) | 1.03 (0.36) | 1.18 (0.41) |
Liver | 4.45 (1.52) | 4.12 (1.69) | 4.26 (1.60) | 4.63 (1.74) | 5.36 (2.01) | 5.89 (2.21) | 6.63 (2.49) |
Spleen | 0.19 (0.04) | 0.17 (0.04) | 0.20 (0.05) | 0.21 (0.05) | 0.22 (0.05) | 0.23 (0.06) | 0.23 (0.06) |
Kidneys | 0.41 (0.14) | 0.37 (0.11) | 0.40 (0.13) | 0.50 (0.16) | 0.51 (0.17) | 0.62 (0.20) | 0.63 (0.20) |
Urinary bladder | 3.10 (0.90) | 2.63 (0.93) | 3.23 (0.97) | 3.54 (1.06) | 3.75 (1.13) | 3.62 (1.09) | 3.90 (1.17) |
Bone marrow | 0.25 (0.09) | 0.14 (0.04) | 0.24 (0.08) | 0.25 (0.08) | 0.23 (0.08) | 0.19 (0.06) | 0.18 (0.06) |
Remainder of body | 30.31 (5.71) | 25.00 (8.46) | 27.47 (7.17) | 26.56 (7.40) | 25.46 (7.73) | 24.63 (8.90) | 23.72 (9.25) |
Whole body | 40.40 (5.93) | 33.78 (9.11) | 37.09 | 37.09 | 37.09 | 37.09 | 37.09 |