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Table 2 Median [1. and 3. quartile] organ- and time-specific effective half-lives (h) of 124I-mIBG in 21 adult patients

From: Biodistribution and radiation dosimetry of 124I-mIBG in adult patients with neural crest tumours and extrapolation to paediatric models

Organ

Effective half-life (h)

Teff, 2 h–4 h

Teff1, 4 h–24 h

Teff2, 24 h–48 h

Teff3, 48–120 h

Salivary glands

NA

19.6 [16.3, 43.0]

23.9 [21.7, 28.3]

24.9 [23.0, 28.3]

Heart wall

NA

16.7 [14.5, 19.2]

20.0 [12.0, 36.0]

28.4 [20.9, 37.5]

Liver

NA

16.9 [13.1, 28.9]

20.4 [14.0, 23.4]

42.8 [30.2, 49.6]

Spleen

NA

31.3 [21.1, 54.2]

25.1 [16.5, 31.6]

34.7 [28.5, 38.7]

Kidneys

NA

17.4 [15.6, 28.0]

26.3 [19.7, 31.9]

36.5 [25.5, 40,6]

Urinary bladder

NA

17.4 [10.7, 29.1]

12.4 [7.7, 20.7]

57.6 [49.2, 72.0]

Blood

7.7 [4.6, 14.2]

16.2 [9.8, 25.6]

27.1 [20.7, 32.0]

29.2 [27.5, 36.3]

Whole-body

9.4 [7.2, 17.9]

23.8 [21.0, 33.3]

25.6 [24.0, 27.3]

30.1 [27.6, 31.0]