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Table 6 Comparison between mean [range] Ki mean values (100ml/ml/min) obtained with IDIF5_7 and PBIF5_7 for pathological (tumor, inflammation) and physiological uptakes

From: Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy

 

Ki (IDIF5_7)

Ki (PBIF5_7)

p value

Tumor (n = 44)

3.07 [0.84; 14.69]

2.87 [0.83; 13.33]

0.586

Immune induced inflammation (n = 11)

1.13 [0.35; 2.30]

1.13 [0.37; 2.04]

0.748

Brain (n = 20)

2.04 [1.21; 3.26]

1.90 [1.15; 2.99]

0.49

Lung (n = 20)

0.11 [0.03; 0.29]

0.10 [0.02; 0.26]

0.81

Aorta (n = 20)

0.38 [0.23; 0.55]

0.36 [0.26; 0.52]

0.59

Heart (n = 20)

2.15 [0.27; 6.39]

2.05 [0.25; 6.34]

0.72

Liver (n = 20)

0.64 [0.49; 1.00]

0.61 [0.41; 0.94]

0.22

Spleen (n = 20)

0.58 [0.37; 1.03]

0.54 [0.35; 0.97]

0.59

Bone (n = 20)

0.63 [0.28; 1.23]

0.61 [0.25; 1.20]

0.54

Muscle (n = 20)

0.17 [0.09; 0.32]

0.17 [0.09; 0.31]

0.51