Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy

EJNMMI Physics

Table 3 Comparison with literature on errors of PBIF AUC regarding on scaling times

Scaling times	Our study (relative to IDIF)	Naganawa et al. [28] (relative to AIF)		Dias et al. [32] (relative to AIF)
	Our study (relative to IDIF)	Naganawa et al. [28] (relative to AIF)		Diabetes no	Diabetes yes
	11–70 min	15–45 min	30–60 min	50–70 min	50–70 min
R²	0.96	0.93	0.94	0.93	0.83
Bias	0.5%	-1%	3%	2%	7%
SD	4%	6%	6%	4%	6%