EJNMMI Physics

Table 1 EC₅₀ (measured in ng/mL) and CV(EC₅₀) are reported as mean ± standard deviation of all the voxels within the region for both phantom and human occupancy data

From: SLIC-Occ: functional segmentation of occupancy images improves precision of EC₅₀ images

	EC₅₀ (ng/mL)			CV(EC₅₀)			Computation time (min)
	Caudate	Putamen	Whole brain	Caudate	Putamen	Whole brain	Computation time (min)
Phantom data
Ground truth	25.00 ± 0.00	50.00 ± 0.00	8.13 ± 3.83	–	–	–
Voxel-level	26.2 ± 10.47	55.25 ± 21.94	8.46 ± 5.27	0.23 ± 0.08	0.22 ± 0.10	0.20 ± 0.06	~ 120^#
Cluster-level	19.92 ± 5.57	41.28 ± 4.97	8.03 ± 3.08	0.03 ± 0.01	0.04 ± 0.01	0.02 ± 0.01	~ 4–8*
Human occupancy study data
Voxel-level	–	–	10.75 ± 8.48	–	–	0.27 ± 0.27
Cluster-level	–	–	9.64 ± 6.03	–	–	0.18 ± 0.12

#Computation time for fitting all the voxels to E_max model
*Computation time for clustering and fitting all clusters to the E_max model. Note that, the time varies depending on the number of clusters (i.e., K)

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