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Table 1 Absorbed doses per administered activity for DOTA-TATE and PSMA-617, labelled to [161Tb] or to [177Lu, expressed in the form of the absorbed dose per unit of activity (Gy/GBq)

From: Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection

Absorbed dose

DOTA-TATE

PSMA-617

[in Gy/GBq]

Tb-161

Lu-177

Tb-161

Lu-177

Kidneys

1.01

0.73

0.89

0.63

Liver

0.28

0.20

0.16

0.11

Salivary glands

0.05

0.04

0.82

0.60

Spleen

3.42

2.44

0.07

0.05

Bone marrow

0.058

0.041

0.077

0.053

10 g Tumour

4.12

2.94

1.10

0.78

1 g Tumour

40.28

28.77

10.81

7.74