From: A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans
Lesion | Time | Full dose group (n = 10) | Half dose group (n = 10) | ||||||
---|---|---|---|---|---|---|---|---|---|
HYPER Iterative | OSEM | Difference (%) | P | HYPER Iterative | OSEM | Difference (%) | P | ||
TBR (large lesion) | 10 s | 7.60 ± 3.37 | 8.27 ± 3.81 | 6.77 ± 9.00 | 0.074 | 10.97 ± 9.09 | 12.25 ± 10.05 | 2.38 ± 34.91 | 0.203 |
30 s | 8.24 ± 2.19 | 7.83 ± 2.41 | 6.58 ± 11.52 | 0.169 | 12.00 ± 10.22 | 10.76 ± 7.96 | 11.17 ± 24.75 | 0.508 | |
1 min | 8.22 ± 2.39 | 7.78 ± 2.57 | 6.99 ± 13.69 | 0.241 | 12.02 ± 11.15 | 10.27 ± 8.07 | 15.15 ± 23.62 | 0.074 | |
2 min | 8.39 ± 2.45 | 7.85 ± 2.46 | 7.55 ± 10.95 | 0.028 | 12.32 ± 11.96 | 10.70 ± 9.87 | 17.63 ± 25.59 | 0.037 | |
3 min | 8.60 ± 2.64 | 8.01 ± 2.53 | 7.67 ± 9.73 | 0.013 | 12.45 ± 12.23 | 10.68 ± 10.01 | 19.40 ± 29.94 | 0.013 | |
4 min | 8.68 ± 2.73 | 8.05 ± 2.60 | 8.31 ± 9.85 | 0.013 | 12.80 ± 12.76 | 10.64 ± 9.73 | 23.13 ± 35.54 | 0.047 | |
5 min | 8.84 ± 2.93 | 8.15 ± 2.75 | 8.69 ± 9.72 | 0.013 | 12.84 ± 12.58 | 10.53 ± 9.15 | 23.39 ± 34.15 | 0.028 | |
TBR (small lesion) | 10 s | 2.10 ± 0.93 | 2.72 ± 1.35 | 7.50 ± 23.64 | 0.074 | 2.50 ± 1.97 | 2.87 ± 2.22 | 4.15 ± 58.74 | 0.445 |
30 s | 2.58 ± 1.88 | 2.43 ± 1.01 | 0.23 ± 31.59 | 0.878 | 3.54 ± 1.99 | 2.77 ± 1.87 | 38.04 ± 58.65 | 0.169 | |
1 min | 2.96 ± 1.55 | 2.37 ± 0.97 | 23.18 ± 29.32 | 0.028 | 4.68 ± 3.06 | 2.77 ± 1.89 | 77.21 ± 63.31 | 0.005 | |
2 min | 3.29 ± 1.69 | 2.47 ± 1.13 | 32.37 ± 22.13 | 0.007 | 4.80 ± 3.42 | 2.70 ± 1.67 | 85.43 ± 77.43 | 0.005 | |
3 min | 3.45 ± 1.90 | 2.53 ± 1.24 | 35.27 ± 20.43 | 0.005 | 4.88 ± 3.46 | 2.68 ± 1.63 | 89.92 ± 77.90 | 0.005 | |
4 min | 3.70 ± 2.01 | 2.60 ± 1.33 | 43.69 ± 21.22 | 0.005 | 4.90 ± 3.35 | 2.70 ± 1.69 | 92.26 ± 75.32 | 0.005 | |
5 min | 3.74 ± 2.13 | 2.60 ± 1.41 | 44.91 ± 23.00 | 0.005 | 4.89 ± 3.19 | 2.71 ± 1.72 | 93.73 ± 76.68 | 0.005 |