From: A proper protocol for routine 18F-FDG uEXPLORER total-body PET/CT scans
Lesion | Time | Full dose group (n = 10) | Half dose group (n = 10) | ||||||
---|---|---|---|---|---|---|---|---|---|
HYPER Iterative | OSEM | Difference (%) | P | HYPER Iterative | OSEM | Difference (%) | P | ||
SUVmax (large lesion) | 10 s | 13.93 ± 6.55 | 14.85 ± 7.10 | 4.51 ± 6.53 | 0.074 | 13.28 ± 3.69 | 14.73 ± 5.40 | 4.15 ± 30.48 | 0.139 |
30 s | 14.83 ± 5.54 | 13.94 ± 6.07 | 8.83 ± 15.03 | 0.139 | 14.06 ± 3.96 | 13.45 ± 4.51 | 6.99 ± 20.83 | 0.333 | |
1 min | 14.69 ± 5.76 | 13.82 ± 6.04 | 8.07 ± 15.01 | 0.114 | 14.22 ± 3.98 | 13.54 ± 4.69 | 7.92 ± 20.44 | 0.203 | |
2 min | 14.65 ± 5.70 | 13.66 ± 5.76 | 8.37 ± 11.80 | 0.017 | 14.29 ± 3.99 | 13.32 ± 5.19 | 12.10 ± 20.79 | 0.047 | |
3 min | 14.82 ± 5.87 | 13.75 ± 5.64 | 8.40 ± 10.57 | 0.009 | 14.28 ± 4.11 | 13.34 ± 5.23 | 11.77 ± 20.66 | 0.047 | |
4 min | 14.94 ± 5.94 | 13.80 ± 5.64 | 8.76 ± 10.54 | 0.013 | 14.39 ± 4.02 | 13.29 ± 5.01 | 12.76 ± 20.87 | 0.047 | |
5 min | 15.08 ± 6.13 | 13.89 ± 5.83 | 9.03 ± 10.61 | 0.013 | 14.45 ± 4.00 | 13.27 ± 4.82 | 12.52 ± 19.20 | 0.047 | |
SUVmax (Small lesion) | 10 s | 3.59 ± 1.30 | 4.73 ± 1.84 | 10.39 ± 47.25 | 0.333 | 3.26 ± 2.09 | 3.85 ± 2.35 | 4.84 ± 68.96 | 0.139 |
30 s | 4.45 ± 2.82 | 4.14 ± 1.35 | 1.82 ± 31.29 | 0.878 | 4.47 ± 1.94 | 3.70 ± 1.89 | 28.21 ± 36.80 | 0.139 | |
1 min | 5.12 ± 2.35 | 4.06 ± 1.36 | 24.19 ± 28.95 | 0.028 | 5.86 ± 1.90 | 3.86 ± 1.91 | 61.46 ± 29.27 | 0.005 | |
2 min | 5.57 ± 2.45 | 4.13 ± 1.53 | 33.30 ± 22.22 | 0.007 | 5.89 ± 1.61 | 3.75 ± 1.87 | 71.70 ± 46.61 | 0.005 | |
3 min | 5.77 ± 2.74 | 4.19 ± 1.69 | 36.11 ± 20.51 | 0.005 | 5.98 ± 1.59 | 3.78 ± 1.89 | 73.96 ± 47.79 | 0.005 | |
4 min | 6.16 ± 2.79 | 4.29 ± 1.81 | 44.17 ± 20.94 | 0.005 | 5.96 ± 1.59 | 3.79 ± 1.95 | 74.27 ± 47.42 | 0.005 | |
5 min | 6.18 ± 2.99 | 4.29 ± 1.94 | 45.21 ± 22.57 | 0.005 | 5.99 ± 1.64 | 3.81 ± 1.99 | 74.96 ± 48.77 | 0.005 |